Bilateral primary intraocular lymphoma, a case report

Primary intraocular lymphoma can occur as an isolated eye tumor or involve both the globe and the central nervous system [I]. Secondary lymphoma may also involve the eye as a result of a systemic tumor [2-51. The syndrome was first recognized in 1951 by Cooper and Riker [6], and numerous cases have been reported since [I-271. The initial term for this non-Hodgkin's lymphoma was reticulum cell sarcoma [I-271. Rappaport reclassified these large cell tumors as histiocytic lymphomas [28]. Recent data demonstrate that these tumors are predominantly large cell lymnhomas and consist of either malignant lymphoma or their precursors [29-3 11. Most commonly, this malignancy occurs in older patients; however, patients as young as 27 years of age have been described [32]. Central nervous system involvement has been reported in approximately 75% of cases and is the usual cause of death [2,3,13,18,32]. A case of lymphocytic lymphomas of both eyes is reported; no such cases have been reported in Thailand before.